Government Cheese is based on Hunter's original short film of the same name. Produced by Apple Studios and Macro Televisions Studios, Government Cheese is written and executive produced by Hunter, who also directs, and Carr. Charles D. King and Ahmadou Seck will executive produce the series for Macro Television Studios along with Jelani Johnson and Marta Fernandez. Oyelowo will executive produce through his Yoruba Saxon banner. Ali Brown will serve as co-executive producer alongside Hunter through Ventureland.

Missick, probably best known for her role as Misty Knight in Marvel's Luke Cage, most recently played the role of Lola Carmichael in the legal drama All Rise, which ran on CBS from 2019 to 2021 and on OWN from 2022 to 2023. Missick was also part of the science fiction drama Altered Carbon. She was also seen in Scandal and Ray Donovan, among others.
Oyelowo and his wife Jessica recently signed a first-look deal with Apple TV+ through their Yoruba Saxon banner to develop and produce for the streamer.