House and the team take on the case of a woman Julia, who is in an open marriage and becomes ill during a date with her on-the-side boyfriend. As perplexing as the case is, Julia's happy and healthy, yet polygamous relationship is equally baffling to the team. Meanwhile, House tests Wilson's relationship with Sam.
Quest roles:
Jennifer Crystal Foley(Rachel Taub), Liz Benoit(Nurse Anne), Danna Brady(Maya), Cynthia Watros(Sam Carr), Charlie Weber(Damien), Sarah Wayne Callies(Julia), Rob Evors(Tom), Jonathan Murphy(Cotter Macklin)