When Jane, Rogelio and Alba learn what is going on with Xo, they all try to comfort her, but Xo insists they let her live her life. Rogelio finally gets River Fields to agree to meet with him, but he learns that River has another plan in mind. Rafael is on a mission to find his sister who may have the information he has been looking for. Meanwhile, Jane is upset with Petra after her girls spill a secret to Mateo.
Quest roles:
Anthony Mendez(Narrator (voice)), Bridget Regan(Rose Solano), Yara Martinez(Dr. Luisa Alver), Mia Allan(Anna), Ella Allan(Ellie Solano), Shelly Bhalla(Krishna Dhawan), Rosario Dawson(Jane Ramos), Gloria Laino(Aida), Brooke Shields(River Fields), Alano Miller(Roman Zazo / Aaron Zazo), Brian Dare(Luca), Kristen Henry King(J.J.), Iyari Limon(Allison), Chloe Fineman(Assistant), Julio Macias(Male Student), Stacey Moseley(Doctor), Alex Smith(Waiter), Julianna Gamiz(5 Year Old Jane), Leigh Bush(Lisa), Sharon Im(Another Student)