Lois' younger sister, Susan, pays the family a visit and brings with her expensive gifts for the boys, biting remarks for Lois and a cold shoulder for Hal – whom she has never forgiven for dumping her for Lois. Lois and Susan's competitive relationship takes a turn for the worse when Susan gives Malcolm and Reese her prize '65 Mustang convertible. But when Lois discovers that Susan needs a kidney transplant, she puts her anger aside and offers to donate her kidney to Susan, which Susan only sees as the perfect opportunity for Lois to one-up her.
Quest roles:
Heather McPhaul(Trish), Laurie Metcalf(Susan), Abigail Mavity(Meagan), Kevin Cooney(Dr. Dumont), Lyndsy Fonseca(Olivia), Jasmine Di Angelo(Brittany), Kate Miner(Katie), Josh Jacobson(Matt), Tianna Danielle Kenney(Buttercup #2), Hayley Erin(Buttercup #1), Alyssa Monka(Buttercup #3), Montana Tsai(Buttercup #4), Gracie Markland(Buttercup #5), Chanel Gaines(Buttercup #6), Barbara Scolaro(Buttercup #7)