Ryan (from "Stray") returns and Clark has to save him from Dr. Garner of the Summerholt Research Facility. Meanwhile, Aunt Nell leaves Smallville, and Lex wants to expand the plant but runs afoul of the mayor.
Quest roles:
William B. Davis(William Tate), Martin Cummins(Lawrence Garner), Sarah-Jane Redmond(Nell Potter), Mitchell Kosterman(Ethan Miller), Mark Gibbon(Mr. Raines), Ryan Kelley(Ryan James), Catherine Lough Haggquist(Mary), Sylvesta Stuart(Orderly), Michael St. John Smith(Dr. Thomas Burton), Robert Seckler(Maintenance Worker)