The Grim Adventures of Billy & Mandy

When Grim cannot take any more abuse from Mandy, Billy tries using Grim's scythe to shrink her to mouse size. Instead of shrinking, Mandy becomes a giant and destroys Billy's house. Although Mandy enjoys being a giant for a while, there are inconveniences, as she keeps growing as time passes, and she wants to return to her normal size. Billy is the only one who can cancel the curse he put on Mandy, and he refuses to do so. Mandy grows bigger than the planet, and she finds herself in the "Realm of the Infinite" with other creatures that grow at infinite pace. Mandy starts bossing them around to please her.