Gary Navarro is arrested for the second attempt to assassinate Dennis Ryland. Knowing she is the key to her mother's survival, Isabelle attempts to kill herself by jumping off the 4400 center building only to survive without a scratch. Matthew Ross expresses his displeasure at her actions and tells her of the destiny she is to face. Isabelle is troubled about what Matthew told her, but after a discussion with Shawn she decides it's her choice with what she does with her life. Matthew gives Isabelle a substance that can kill her if it's injected.
Quest roles:
Peter Coyote(Dennis Ryland), Kavan Smith(Agent Garrity), Jeffrey Combs(Kevin Burkhardt), Richard Kahan(Marco Pacella), Sharif Atkins(Gary Navarro), Garret Dillahunt, Ian Tracey(Daniel Armand), Fred Henderson, Olivia Cheng, Andrew Kavadas, Frank Cassini, Tippi Hedren, Leanne Adachi(Nurse), Peter Bryant(Agent Wood), Daniel Pepper(NTAC Hallway Guard), Donna Soares(NTAC Medical Nurse), Khaira Ledeyo(Reporter)