As Chuck is beginning to adapt to his new life as a spy, a doctor who could possibly "cure" Chuck is murdered. Chuck then begins a high-speed fight for his life, all while trying to decide which of his two new colleagues might be out to get him. Meanwhile, Chuck's sister Ellie invites Sarah to dinner to meet the family.
Quest roles:
Vik Sahay(Lester Patel), Scott Krinsky(Jeff Barnes), Ryan McPartlin(Devon Woodcomb), Mark Christopher Lawrence(Big Mike), Bonita Friedericy(Diane Beckman), C.S. Lee(Harry Tang), Tony Todd(CIA Director Graham), John Fleck(Dr. Jonas Zarnow), Max Prado(Teenage Boy)